Effect of a plant-tissue preparation on immunometabolic parameters in horses kept within the East Ural Radioactive Trace zone

Abstract

Introduction. Human impact on the environment negatively affects animal health and productivity. Despite existing solutions involving the use of immunometabolic agents, their application does not always account for the combined effect of various anthropogenic factors on the immune status and metabolism of animals, necessitating the development of new comprehensive approaches.
Aim. To investigate the role of negative anthropogenic environmental factors in the pathogenesis of infectious diseases in animals and to develop methods for correcting their cumulative negative impact on immunity and metabolic processes using Vidoral plant-tissue preparation.
Materials and methods. The study involved working crossbred horses from a farm in the Kamyshlov district of the Sverdlovsk Region, Russia, located within the East Ural Radioactive Trace (EURT) zone. The research was based on the analysis of official data from State Reports on the Environmental Conditions of the Sverdlovsk Region (2010–2024) and over 250 scientific publications dedicated to the influence of anthropogenic factors on the pathogenesis of animal diseases. The efficacy of the immunometabolic Vidoral preparation for enhancing immune status, optimizing metabolic processes, and improving animal survival rates was assessed through morphological, haematological, biochemical, and immunological parameters in the horses.
Results. The administration of the developed Vidoral preparation demonstrated a corrective effect on the negative impact of anthropogenic environmental factors, namely: normalization of erythrocyte sedimentation rate, mineral metabolism, liver and kidney function, as well as enhancement of the immune status in horses. The preparation showed high efficacy, exhibiting nephroprotective, hepatoprotective, and anti-inflammatory actions.
Conclusion. The study results are of practical importance for the agricultural sector in environmentally compromised regions, as they provide a ready-to-implement solution for enhancing the productive health of livestock.

To cite: Alekseev A.D. Effect of a plant-tissue preparation on the immunometabolic parameters of horses kept in the East Ural Radioactive Trace Zone. Agrarian Bulletin of the North Caucasus. 2025;15(4):10-23. https://doi.org/10.31279/2949-4796-2025-15-4-10-23